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Scientific Validation

Peer-reviewed. Regulator-accepted. Globally cited.

Every PV instrument is backed by peer-reviewed publications and accepted by FDA, EMA, PMDA, and other major regulators as primary endpoint tools. Our equipment has been used in ETDRS, AREDS, DRCR.net, and most major retinal and vision clinical trials of the last thirty years.

200+
Citations
Peer-reviewed publications referencing PV instruments
FDA · EMA · PMDA
Accepted
PV instruments accepted as primary endpoint tools across major regulators
47-site
CV analysis
Multi-site coefficient of variation reproducibility data on request
NIST
Calibration
Traceable calibration with documented audit trail per shipment

PRODUCT CATEGORIES

Vision testing instruments engineered for measurement integrity.

Six instrument families covering visual acuity, contrast sensitivity, color vision, low vision, reading speed, and pediatric testing. Every product validated and peer-reviewed.

Visual Acuity Charts

ETDRS Revised 2000, Sloan Letters, HOTV, Lea Symbols, and pediatric optotypes. The standard for retinal trials, ophthalmology research, and clinical practice for over 50 years.

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Contrast Sensitivity

Pelli-Robson, Mars, and validated contrast sensitivity panels. Sensitive to early visual function changes that standard acuity testing misses.

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Reading Speed (iReST)

International Reading Speed Texts validated for low vision research and clinical assessment in seventeen languages. Tablet and print formats.

Browse iReST →

Low Vision Testing

Specialized instruments for severely impaired vision: enhanced contrast, simplified optotypes, validated low-vision protocols.

Browse low vision →

Pediatric Vision Testing

LEA Symbols, Teller Acuity Cards, HOTV, and shape-based optotypes for pre-literate and developmentally diverse populations.

Browse pediatric →

Clinical Trial Solutions

End-to-end ophthalmic trial infrastructure: certified equipment, investigator certification, training, and centralized quality monitoring.

Explore CTS →

Peer-Reviewed Publications

200+ citations across optometry, ophthalmology, and vision research literature. Validation studies for every major instrument family.

Regulatory Acceptance

FDA, EMA, PMDA, and other regulators accept PV instruments as primary endpoint tools in ophthalmic and neurology clinical trials.

Multi-Site Validation

Coefficient of variation reported across 47-site trials, with documented reproducibility data available for sponsor regulatory teams on request.

Calibration Standards

NIST-traceable calibration with documented procedures and audit trail. Every chart, every cabinet, every instrument.

THE PRECISION VISION STORY

Gold Standard

Regulatory affairs teams need cite-ready evidence: peer-reviewed publication index, regulator acceptance documentation, methodology white papers, and per-instrument validation studies. We maintain these packages continuously, not on demand. Send us your evidence file requirements and we'll send the package within five business days. Pre-submission consultation available for novel trial protocols.

Watch our story
Manufacturing in Woodstock, IL
CASE FILE · MULTI-SITE CV ANALYSIS

How we report between-site coefficient of variation.

For sponsor and regulatory teams building evidence files, the most-requested documentation package is our multi-site coefficient of variation analysis. PV measures and reports between-site CV across active trials and publishes the methodology behind the numbers.

"The CV reporting methodology is more transparent than what most measurement vendors will share. We included it verbatim in our regulatory submission."
Regulatory Affairs DirectorSponsor (anonymized) · FDA submission 2024
3.1%
CV across 47 sites · Phase III GA
5 days
Documentation turnaround
Open
Methodology disclosure to regulators
Request the binder
Validation Evidence Binder · v4.2

The Validation Evidence Binder

PDF · 64 pp · Updated April 2026
01 Peer-reviewed citation index — ETDRS, AREDS, DRCR.net references
02 FDA, EMA, PMDA acceptance documentation
03 Methodology white papers (ETDRS, Pelli-Robson, iReST)
04 Per-instrument validation studies
05 Multi-site coefficient of variation analysis & reproducibility data
06 Editable evidence-citation table for sponsor submissions
PRECISION VISION Confidential · 2026
DOWNLOAD · VALIDATION PACKAGE

Built for your evidence file.

Used by sponsor regulatory teams as the credibility appendix in clinical trial submissions. Cite-ready references, peer-reviewed publication index, and per-instrument validation studies.

Used only to send you the package and follow up if you have questions. We do not share or sell your information.

Scientific Validation & Training

Scientific Validation & Training

What is scientific validation in vision testing?

Scientific validation refers to standardized methodologies designed to support reliable, reproducible, and clinically trusted visual assessment outcomes.

Why is standardization important in visual assessment?

Standardization helps improve consistency, reproducibility, and reliability across testing environments and patient evaluations.

Does Precision Vision provide training and certification?

Yes. Precision Vision supports examiner training, certification, lane standardization, and standardized visual assessment methodologies.

What types of training does Precision Vision support?

Training support includes:

ETDRS methodologies

BCVA assessment

Examiner alignment

Functional vision assessment

Lane certification

Standardized testing procedures